CACNB2 Antibody - middle region : Biotin (ARP35597_P050-Biotin)

Product Specifications

Gene Name

Calcium channel, voltage-dependent, beta 2 subunit

Gene Aliases

CAB2, MYSB, CAVB2, CACNLB2

Gene ID

783

Swiss Prot

Q08289

Accession Number

NP_963884

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CACNB2

Target

CACNB2 contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. Defects in CACNB2 are the cause of Brugada syndrome type 4 (BRS4) .

Partner Proteins

REM1; PRKACA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Guinea Pig: 86%; Human: 100%; Mouse: 92%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.