CACNB2 Antibody - middle region : FITC (ARP35597_P050-FITC)
Product Specifications
Gene Name
Calcium channel, voltage-dependent, beta 2 subunit
Gene Aliases
CAB2, MYSB, CAVB2, CACNLB2
Gene ID
783
Swiss Prot
Q08289
Accession Number
NP_963884
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Guinea Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human CACNB2
Target
CACNB2 contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. Defects in CACNB2 are the cause of Brugada syndrome type 4 (BRS4) .
Partner Proteins
REM1; PRKACA
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 86%; Guinea Pig: 86%; Human: 100%; Mouse: 92%; Rabbit: 93%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
68kDa
References & Citations
Uhl, G.R., (2008) Arch. Gen. Psychiatry 65 (6), 683-693
Shipping Conditions
Wet Ice
Protein Length
605
NCBI Gene Symbol
CACNB2
NCBI GB Accession Number
CACNB2
Host or Source
Rabbit
Protein Name
Voltage-dependent L-type calcium channel subunit beta-2
Nucleotide Accession Number
NM_201590
Peptide Sequence
HLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGD
Subunit
Beta-2
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