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CACNB2 Antibody - middle region : Biotin (ARP35594_P050-Biotin)

Product Specifications

Gene Name

Calcium channel, voltage-dependent, beta 2 subunit

Gene Aliases

CAB2, MYSB, CAVB2, CACNLB2

Gene ID

783

Swiss Prot

A6PVM7

Accession Number

NP_963866

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CACNB2

Target

CACNB2 belongs to the calcium channel beta subunit family.The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.Defects in CACNB2 are the cause of Brugada syndrome type 4 (BRS4) .

Partner Proteins

REM1; PRKACA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 93%; Zebrafish: 82%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

68kDa

References & Citations

Uhl, G.R., (2008) Arch. Gen. Psychiatry 65 (6), 683-693

Shipping Conditions

Wet Ice

Protein Length

608

NCBI Gene Symbol

CACNB2

NCBI GB Accession Number

CACNB2

Host or Source

Rabbit

Protein Name

Calcium channel, voltage-dependent, beta 2 subunit EMBL CAO03605.1

Nucleotide Accession Number

NM_201572

Peptide Sequence

DACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQG

Subunit

Beta-2

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