NUDT9 Antibody - N-terminal region : Biotin (ARP35539_P050-Biotin)
Product Specifications
Gene Name
Nudix (nucleoside diphosphate linked moiety X) -type motif 9
Gene Aliases
NUDT10
Gene ID
53343
Swiss Prot
Q9BW91
Accession Number
NP_076952
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human NUDT9
Target
Human ADP-ribose pyrophosphatase NUDT9 belongs to a superfamily of Nudix hydrolases that catabolize potentially toxic compounds in the cell. NUDT9 alpha protein is targeted highly specifically to mitochondria, whereas the predicted protein of the NUDT9 beta transcript, which is missing this sequence, exhibits no clear subcellular localization. Investigation of the physical and enzymatic properties of NUDT9 indicates that it is functional as a monomer, optimally active at near neutral pH, and that it requires divalent metal ions and an intact Nudix motif for enzymatic activity.
Partner Proteins
EPHA2; APP; GLOD4
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 92%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
39kDa
References & Citations
Otsuki, T., et al., (2005) DNA Res. 12 (2), 117-126
Shipping Conditions
Wet Ice
Protein Length
350
NCBI Gene Symbol
NUDT9
NCBI GB Accession Number
NUDT9
Host or Source
Rabbit
Protein Name
ADP-ribose pyrophosphatase, mitochondrial
Nucleotide Accession Number
NM_024047
Peptide Sequence
SPKFNEKDGHVERKSKNGLYEIENGRPRNPAGRTGLVGRGLLGRWGPNHA
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