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NUDT9 Antibody - N-terminal region : FITC (ARP35539_P050-FITC)

Selected Variant

ARP35539_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Nudix (nucleoside diphosphate linked moiety X) -type motif 9

Gene Aliases

NUDT10

Gene ID

53343

Swiss Prot

Q9BW91

Accession Number

NP_076952

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NUDT9

Target

Human ADP-ribose pyrophosphatase NUDT9 belongs to a superfamily of Nudix hydrolases that catabolize potentially toxic compounds in the cell. NUDT9 alpha protein is targeted highly specifically to mitochondria, whereas the predicted protein of the NUDT9 beta transcript, which is missing this sequence, exhibits no clear subcellular localization. Investigation of the physical and enzymatic properties of NUDT9 indicates that it is functional as a monomer, optimally active at near neutral pH, and that it requires divalent metal ions and an intact Nudix motif for enzymatic activity.

Partner Proteins

EPHA2; APP; GLOD4

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

39kDa

References & Citations

Otsuki, T., et al., (2005) DNA Res. 12 (2), 117-126

Shipping Conditions

Wet Ice

Protein Length

350

NCBI Gene Symbol

NUDT9

NCBI GB Accession Number

NUDT9

Host or Source

Rabbit

Protein Name

ADP-ribose pyrophosphatase, mitochondrial

Nucleotide Accession Number

NM_024047

Peptide Sequence

SPKFNEKDGHVERKSKNGLYEIENGRPRNPAGRTGLVGRGLLGRWGPNHA

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