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HTR3E Antibody - middle region : FITC (ARP35532_P050-FITC)

Product Specifications

Gene Name

5-hydroxytryptamine (serotonin) receptor 3E, ionotropic

Gene Aliases

5-HT3E, 5-HT3-E, 5-HT3c1

Gene ID

285242

Swiss Prot

A5X5Y0

Accession Number

NP_872395

Host

Rabbit

Reactivity

Human, Dog, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HTR3E

Target

HTR3E belongs to the ligand-gated ion channel receptor superfamily. HTR3E is a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IF, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 100%; Horse: 83%; Human: 100%; Rabbit: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

53kDa

References & Citations

Peters, J.A., Biochem. Soc. Trans. 32 (PT3), 547-552 (2004)

Shipping Conditions

Wet Ice

Protein Length

471

NCBI Gene Symbol

HTR3E

NCBI GB Accession Number

HTR3E

Host or Source

Rabbit

Protein Name

5-hydroxytryptamine receptor 3E

Nucleotide Accession Number

NM_182589

Peptide Sequence

RWLHSLLLHCNSPGRCCPTAPQKENKGPGLTPTHLPGVKEPEVSAGQMPG

Frequently Asked Questions

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