P2RX7 Antibody - middle region: Biotin (ARP35517_P050-Biotin)
Product Specifications
Gene Name
Purinergic receptor P2X, ligand-gated ion channel, 7
Gene Aliases
P2X7
Gene ID
5027
Swiss Prot
Q99572
Accession Number
NP_803176
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human P2RX7
Target
The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.
Partner Proteins
KRTAP10-8; KRT31; TM9SF1; CASK; EFNB3; EMP3; PANX1; SVIL; ACTB
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 79%; Dog: 79%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 79%; Rabbit: 90%; Rat: 85%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
69kDa
Shipping Conditions
Wet Ice
Protein Length
595
NCBI Gene Symbol
P2RX7
Protein Name
P2X purinoceptor 7
Nucleotide Accession Number
NM_177427
Curated Selection
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