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GRIK2 Antibody - C-terminal region : FITC (ARP35516_P050-FITC)

Selected Variant

ARP35516_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Glutamate receptor, ionotropic, kainate 2

Gene Aliases

EAA4, GLR6, MRT6, GLUK6, GLUR6, GluK2

Gene ID

2898

Swiss Prot

Q13002-3

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human GRIK2

Target

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation.

Partner Proteins

CALCOCO1; TRIM25; PICK1; DLG4; LIN7B; GRID2; PRKAA1; SDCBP; CTNND1; DLG1; GRIK5; GRIK4; DLG3; CASK; GRIA1; GRIK2; CTNNB1; CDH2; GRIP1; GRIA2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

64kDa

Shipping Conditions

Wet Ice

Protein Length

548

NCBI Gene Symbol

GRIK2

NCBI GB Accession Number

GRIK2

Host or Source

Rabbit

Protein Name

Glutamate receptor, ionotropic kainate 2

Peptide Sequence

YEIRLVEDGKYGAQDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVI

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