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P2RX4 Antibody - N-terminal region : FITC (ARP35512_P050-FITC)

Product Specifications

Gene Name

Purinergic receptor P2X, ligand-gated ion channel, 4

Gene Aliases

P2X4, P2X4R

Gene ID

5025

Swiss Prot

Q99571

Accession Number

NP_002551

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human P2RX4

Target

P2RX4 is the receptor for ATP that acts as a ligand gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin.The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants have been identified for this gene although their full-length natures have not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

NOTCH2NL; PIH1D3; KRTAP5-9; WNT4; MCM2; CDH5

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 86%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

43kDa

References & Citations

An, W.F., (2007) Mol. Pharmacol. 72 (6), 1402-1405

Shipping Conditions

Wet Ice

Protein Length

388

NCBI Gene Symbol

P2RX4

NCBI GB Accession Number

P2RX4

Host or Source

Rabbit

Protein Name

P2X purinoceptor 4

Nucleotide Accession Number

NM_002560

Peptide Sequence

VQLLILAYVIGWVFVWEKGYQETDSVVSSVTTKVKGVAVTNTSKLGFRIW

Frequently Asked Questions

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