KCNIP2 Antibody - N-terminal region : Biotin (ARP35498_P050-Biotin)
Product Specifications
Gene Name
Kv channel interacting protein 2
Gene Aliases
KCHIP2
Gene ID
30819
Swiss Prot
Q9NS61-6
Accession Number
NP_055406
Host
Rabbit
Reactivity
Human, Dog, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human KCNIP2
Target
KCNIP2 encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene.
Partner Proteins
KCND2; KCNIP1; KCNIP2; KCNE4; KCND3; KCNIP4
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Dog: 86%; Human: 100%; Rabbit: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
32kDa
References & Citations
Han, W., (2006) J. Biol. Chem. 281 (37), 27134-27144
Shipping Conditions
Wet Ice
Protein Length
285
NCBI Gene Symbol
KCNIP2
NCBI GB Accession Number
KCNIP2
Host or Source
Rabbit
Protein Name
Kv channel-interacting protein 2
Nucleotide Accession Number
NM_014591
Peptide Sequence
LKQRFLKLLPCCGPQALPSVSEIGRVFRFLGDSSLPSALAAPASLRPHRP
Frequently Asked Questions
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