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KCNH2 Antibody - C-terminal region : FITC (ARP35450_P050-FITC)

Product Specifications

Gene Name

Potassium voltage-gated channel, subfamily H (eag-related), member 2

Gene Aliases

ERG1, HERG, LQT2, SQT1, ERG-1, H-ERG, HERG1, Kv11.1

Gene ID

3757

Swiss Prot

Q12809-2

Accession Number

NP_742054

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of human KCNH2

Target

This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2) .This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2) . Transcript variants encoding distinct isoforms have been identified.

Partner Proteins

UBC; NEDD4L; STUB1; HSP90AA1; RAB11A; FKBP8; STIP1; BAG2; HSPA8; DNAJA1; CANX; CALR; CUL1; CAV3; HSPA4; ALG10B; NDUFS6; ALG10; CDC73; YWHAE; KCNE2; RHOH; PRKACA; KCNE1; YWHAH

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

90kDa

References & Citations

Nagaoka, I., (2008) Circ. J. 72 (5), 694-699

Shipping Conditions

Wet Ice

Protein Length

819

NCBI Gene Symbol

KCNH2

NCBI GB Accession Number

KCNH2

Host or Source

Rabbit

Protein Name

Potassium voltage-gated channel subfamily H member 2

Nucleotide Accession Number

NM_172057

Peptide Sequence

SQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPG

Frequently Asked Questions

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