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KCNMB3 Antibody - middle region : Biotin (ARP35444_P050-Biotin)

Product Specifications

Gene Name

Potassium large conductance calcium-activated channel, subfamily M beta member 3

Gene Aliases

HBETA3, KCNMB2, KCNMBL, BKBETA3, SLOBETA3, SLO-BETA-3, K (VCA) BETA-3

Gene ID

27094

Swiss Prot

Q9NPA1-2

Accession Number

NP_741979

Host

Rabbit

Reactivity

Human, Rat, Dog

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human KCNMB3

Target

KCNMB3 is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. At least four transcript variants encoding four different isoforms have been found for KCNMB3.MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. At least four transcript variants encoding four different isoforms have been found for this gene.

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 91%; Human: 100%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

31kDa

References & Citations

Lorenz, S., (2007) Am. J. Med. Genet. B Neuropsychiatr. Genet. 144 (1), 10-13

Shipping Conditions

Wet Ice

Protein Length

277

NCBI Gene Symbol

KCNMB3

NCBI GB Accession Number

KCNMB3

Host or Source

Rabbit

Protein Name

Calcium-activated potassium channel subunit beta-3

Nucleotide Accession Number

NM_171828

Peptide Sequence

SLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQFKLC

Subunit

Beta-3

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