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TRPV4 Antibody - middle region : Biotin (ARP35416_P050-Biotin)

Product Specifications

Gene Name

Transient receptor potential cation channel, subfamily V, member 4

Gene Aliases

SMAL, VRL2, BCYM3, CMT2C, SPSMA, TRP12, VROAC, HMSN2C, OTRPC4, SSQTL1

Gene ID

59341

Swiss Prot

Q9HBA0-2

Accession Number

NP_671737

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TRPV4

Target

TRPV4 is a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. TRPV4 is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure.This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Two transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

UBC; ARRB2; KRIT1; ITCH; PACSIN3; PACSIN1; TRPV4; PACSIN2; MAP7; SRC; LYN; YES1; LCK; HCK; FYN; CALM1; OS9; PACS1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

TRPV4 is supported by BioGPS gene expression data to be expressed in PANC1

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 86%; Guinea Pig: 86%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

91kDa

References & Citations

Fischer, W.H. (er) Pflugers Arch. (2008) In press

Shipping Conditions

Wet Ice

Protein Length

811

NCBI Gene Symbol

TRPV4

NCBI GB Accession Number

TRPV4

Host or Source

Rabbit

Protein Name

Transient receptor potential cation channel subfamily V member 4

Nucleotide Accession Number

NM_147204

Peptide Sequence

RVDEVNWSHWNQNLGIINEDPGKNETYQYYGFSHTVGRLRRDRWSSVVPR

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