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HTR3C Antibody - middle region : FITC (ARP35391_P050-FITC)

Selected Variant

ARP35391_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

5-hydroxytryptamine (serotonin) receptor 3C, ionotropic

Gene ID

170572

Swiss Prot

Q8WXA8

Accession Number

NP_570126

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HTR3C

Target

HTR3C is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3.

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

50kDa

References & Citations

Fasching, P.A., (er) J. Cancer Res. Clin. Oncol. (2008) In press

Shipping Conditions

Wet Ice

Protein Length

447

NCBI Gene Symbol

HTR3C

NCBI GB Accession Number

HTR3C

Host or Source

Rabbit

Protein Name

5-hydroxytryptamine receptor 3C

Nucleotide Accession Number

NM_130770

Peptide Sequence

CCPTAPQKGNKGLGLTLTHLPGPKEPGELAGKKLGPRETEPDGGSGWTKT

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