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TRPC4 Antibody - middle region : HRP (ARP35256_P050-HRP)

Product Specifications

Gene Name

Transient receptor potential cation channel, subfamily C, member 4

Gene Aliases

TRP4, HTRP4, HTRP-4

Gene ID

7223

Swiss Prot

Q9UBN4

Accession Number

NP_057263

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TRPC4

Target

TRPC4 is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC4 probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. It has also been shown to be calcium-selective. TRPC4 may also be activated by intracellular calcium store depletion.

Partner Proteins

UBC; TRPC4AP; TNFRSF1A; TRPC1; ITCH; SLC9A3R1; TJP1; ITPR2; TRPC5; ITPR3; ITPR1; MX1; TRPC4; TRPC6; TRPC3; HOMER3

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 82%; Horse: 77%; Human: 100%; Mouse: 100%; Pig: 85%; Rabbit: 100%; Rat: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

112kDa

References & Citations

Odell, A.F., (2008) J. Biol. Chem. 283 (7), 4395-4407

Shipping Conditions

Wet Ice

Protein Length

977

NCBI Gene Symbol

TRPC4

NCBI GB Accession Number

TRPC4

Host or Source

Rabbit

Protein Name

Short transient receptor potential channel 4

Nucleotide Accession Number

NM_016179

Peptide Sequence

CPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYDLNLPDTVTHEDYVTTRL

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