MLC1 Antibody - middle region : Biotin (ARP35249_P050-Biotin)

Product Specifications

Gene Name

Megalencephalic leukoencephalopathy with subcortical cysts 1

Gene Aliases

VL, LVM, MLC

Gene ID

23209

Swiss Prot

Q15049

Accession Number

NP_055981

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human MLC1

Target

MLC1 may be a transporter. It may act as a non-selective neuronal cation channel.The function of this gene product is unknown; however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.

Partner Proteins

KDM1A; PRMT6; Cav2; Dtnb; Snta1; Dtna; Tuba1a; Kcnj10; Cav1; UBC; TPT1; DAPK2; MYLK

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 91%; Dog: 86%; Guinea Pig: 92%; Horse: 86%; Human: 100%; Mouse: 93%; Rabbit: 83%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

41kDa

References & Citations

Ambrosini, E., (2008) Mol. Cell. Neurosci. 37 (3), 480-493

Shipping Conditions

Wet Ice

Protein Length

377

NCBI Gene Symbol

MLC1

NCBI GB Accession Number

MLC1

Host or Source

Rabbit

Protein Name

Membrane protein MLC1

Nucleotide Accession Number

NM_015166

Peptide Sequence

SDSANILDEVPFPARVLKSYSVVEVIAGISAVLGGIIALNVDDSVSGPHL

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