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KCNIP2 Antibody - N-terminal region : HRP (ARP35245_P050-HRP)

Product Specifications

Gene Name

Kv channel interacting protein 2

Gene Aliases

KCHIP2

Gene ID

30819

Swiss Prot

Q9NS61-6

Accession Number

NP_055406

Host

Rabbit

Reactivity

Human, Dog, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human KCNIP2

Target

KCNIP2 encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene.

Partner Proteins

KCND2; KCNIP1; KCNIP2; KCNE4; KCND3; KCNIP4

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 86%; Human: 100%; Rabbit: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

32kDa

References & Citations

Han, W., (2006) J. Biol. Chem. 281 (37), 27134-27144

Shipping Conditions

Wet Ice

Product Datasheet

Anti-KCNIP2 (ARP35245_P050-HRP) antibody

Protein Length

285

NCBI Gene Symbol

KCNIP2

NCBI GB Accession Number

KCNIP2

Host or Source

Rabbit

Protein Name

Kv channel-interacting protein 2

Nucleotide Accession Number

NM_014591

Peptide Sequence

LKQRFLKLLPCCGPQALPSVSEIGRVFRFLGDSSLPSALAAPASLRPHRP

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