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SCN8A Antibody - C-terminal region : HRP (ARP35228_P050-HRP)

Product Specifications

Gene Name

Sodium voltage-gated channel alpha subunit 8

Gene Aliases

MED, PN4, CIAT, BFIS5, DEE13, NaCh6, CERIII, EIEE13, MYOCL2, Nav1.6

Gene ID

6334

Swiss Prot

Q9UQD0

Accession Number

NP_001171455.1

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of human SCN8A

Target

This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

52kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-SCN8A (ARP35228_P050-HRP) antibody

Protein Length

475

NCBI Gene Symbol

SCN8A

NCBI GB Accession Number

SCN8A

Host or Source

Rabbit

Protein Name

Sodium channel protein type 8 subunit alpha

Nucleotide Accession Number

NM_001177984.2

Peptide Sequence

KSSIFSFRGPGRFRDPGSENEFADDEHSTVEESEGRRDSLFIPIRARERR

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