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KCNA10 Antibody - middle region : HRP (ARP35178_T100-HRP)

Selected Variant

ARP35178_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

Potassium voltage-gated channel, shaker-related subfamily, member 10

Gene Aliases

Kcn1, Kv1.8

Gene ID

3744

Swiss Prot

Q16322

Accession Number

NP_005540

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human KCNA10

Target

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Four sequence-related potassium channel genes, shaker, shaw, shab, and shal, have been identified in Drosophila, and each has been shown to have human homolog (s) . KCNA10 encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP.

Partner Proteins

POMP

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 92%; Guinea Pig: 92%; Human: 100%; Mouse: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

56kDa

References & Citations

Yao, X., et al., (2002) J. Am. Soc. Nephrol. 13 (12), 2831-2839

Shipping Conditions

Wet Ice

Protein Length

511

NCBI Gene Symbol

KCNA10

NCBI GB Accession Number

KCNA10

Host or Source

Rabbit

Protein Name

Potassium voltage-gated channel subfamily A member 10

Nucleotide Accession Number

NM_005549

Peptide Sequence

PANVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFW

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