TRPC6 Antibody - middle region : FITC (ARP35144_P050-FITC)

Product Specifications

Gene Name

Transient receptor potential cation channel, subfamily C, member 6

Gene Aliases

TRP6, FSGS2

Gene ID

7225

Swiss Prot

Q9Y210

Accession Number

NP_004612

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TRPC6

Target

TRPC6 forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2) .

Partner Proteins

RNF24; TRPC3; ORAI1; TRPM2; TRPC6; SRC; ITPR3; MX1; FYN; TRPC7; TRPC5; TRPC4; TRPC1; TRPC2; ITPR1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 85%; Pig: 100%; Rat: 77%; Yeast: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.