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CLCNKA Antibody - N-terminal region : FITC (ARP35132_P050-FITC)

Selected Variant

ARP35132_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Chloride channel, voltage-sensitive Ka

Gene Aliases

CLCK1, ClC-K1, hClC-Ka

Gene ID

1187

Swiss Prot

P51800

Accession Number

NP_004061

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CLCNKA

Target

CLCNKA is a member of the CLC family of voltage-gated chloride channels. It is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 90%; Human: 100%; Mouse: 85%; Pig: 85%; Rat: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

75kDa

References & Citations

Kramer, B.K., (2008) Nat Clin Pract Nephrol 4 (1), 38-46

Shipping Conditions

Wet Ice

Protein Length

687

NCBI Gene Symbol

CLCNKA

NCBI GB Accession Number

CLCNKA

Host or Source

Rabbit

Protein Name

Chloride channel protein ClC-Ka

Nucleotide Accession Number

NM_004070

Peptide Sequence

MEELVGLREGFSGDPVTLQELWGPCPHIRRAIQGGLEWLKQKVFRLGEDW

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