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KCNN4 Antibody - C-terminal region : FITC (ARP35098_P050-FITC)

Product Specifications

Gene Name

Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4

Gene Aliases

IK, IK1, SK4, DHS2, KCA4, hSK4, IKCA1, hKCa4, KCa3.1, hIKCa1

Gene ID

3783

Swiss Prot

O15554

Accession Number

NP_002241

Host

Rabbit

Reactivity

Human, Rat, Cow, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human KCNN4

Target

KCNN4 is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. KCNN4 may be part of the predominant calcium-activated potassium channel in T-lymphocytes. The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

UBC; RAB7A; TSG101; Cam; CALM1; USP8; PRKAG1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 92%; Horse: 92%; Human: 100%; Pig: 83%; Rat: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

48kDa

References & Citations

Gao, Y., (2008) J. Biol. Chem. 283 (14), 9049-9059

Shipping Conditions

Wet Ice

Product Datasheet

Anti-KCNN4 (ARP35098_P050-FITC) antibody

Protein Length

427

NCBI Gene Symbol

KCNN4

NCBI GB Accession Number

KCNN4

Host or Source

Rabbit

Protein Name

Intermediate conductance calcium-activated potassium channel protein 4

Nucleotide Accession Number

NM_002250

Peptide Sequence

DLQQNLSSSHRALEKQIDTLAGKLDALTELLSTALGPRQLPEPSQQSK

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