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GRIN2C Antibody - N-terminal region : Biotin (ARP35016_P050-Biotin)

Product Specifications

Gene Name

Glutamate receptor, ionotropic, N-methyl D-aspartate 2C

Gene Aliases

NR2C, GluN2C, NMDAR2C

Gene ID

2905

Swiss Prot

Q14957

Accession Number

NP_000826

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GRIN2C

Target

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D) .

Partner Proteins

ERBB2IP; DLGAP1; INADL; IL16; DLG4; DLG3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Sample Type

GRIN2C is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

136kDa

References & Citations

Self, R.L., et al., (2004) Brain Res. 995 (1), 39-45

Shipping Conditions

Wet Ice

Protein Length

1233

NCBI Gene Symbol

GRIN2C

NCBI GB Accession Number

GRIN2C

Host or Source

Rabbit

Protein Name

Glutamate [NMDA] receptor subunit epsilon-3

Nucleotide Accession Number

NM_000835

Peptide Sequence

VNTTNPSSLLTQICGLLGAAHVHGIVFEDNVDTEAVAQILDFISSQTHVP

Subunit

Epsilon-3

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