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GABRB2 Antibody - N-terminal region : Biotin (ARP34988_P050-Biotin)

Product Specifications

Gene Name

Gamma-aminobutyric acid (GABA) A receptor, beta 2

Gene Aliases

DEE92, ICEE2

Gene ID

2561

Swiss Prot

P47870

Accession Number

NP_000804

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GABRB2

Target

The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion.

Partner Proteins

UBC; UBQLN1; TRAK2; ARFGEF2; PRKCB; PPP3CA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

54kDa

References & Citations

Inada, T., (2008) Pharmacogenet. Genomics 18 (4), 317-323

Shipping Conditions

Wet Ice

Protein Length

474

NCBI Gene Symbol

GABRB2

NCBI GB Accession Number

GABRB2

Host or Source

Rabbit

Protein Name

Gamma-aminobutyric acid receptor subunit beta-2

Nucleotide Accession Number

NM_000813

Peptide Sequence

DNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTT

Subunit

Beta-2

Frequently Asked Questions

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