GABRA4 Antibody - N-terminal region : Biotin (ARP34982_P050-Biotin)
Product Specifications
Gene Name
Gamma-aminobutyric acid (GABA) A receptor, alpha 4
Gene ID
2557
Swiss Prot
P48169
Accession Number
NP_000800
Host
Rabbit
Reactivity
Human, Rat, Cow, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human GABRA4
Target
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
DGAT1; APP; PRKCG
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 86%; Horse: 79%; Human: 100%; Rabbit: 93%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
58kDa
References & Citations
Agrawal, A., (2008) Addiction 103 (6), 1027-1038
Shipping Conditions
Wet Ice
Protein Length
554
NCBI Gene Symbol
GABRA4
NCBI GB Accession Number
GABRA4
Host or Source
Rabbit
Protein Name
Gamma-aminobutyric acid receptor subunit alpha-4
Nucleotide Accession Number
NM_000809
Peptide Sequence
MVSAKKVPAIALSAGVSFALLRFLCLAVCLNESPGQNQKEEKLCTENFTR
Subunit
Alpha-4
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