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GABRA4 Antibody - N-terminal region : Biotin (ARP34982_P050-Biotin)

Product Specifications

Gene Name

Gamma-aminobutyric acid (GABA) A receptor, alpha 4

Gene ID

2557

Swiss Prot

P48169

Accession Number

NP_000800

Host

Rabbit

Reactivity

Human, Rat, Cow, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GABRA4

Target

GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

DGAT1; APP; PRKCG

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Horse: 79%; Human: 100%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

58kDa

References & Citations

Agrawal, A., (2008) Addiction 103 (6), 1027-1038

Shipping Conditions

Wet Ice

Protein Length

554

NCBI Gene Symbol

GABRA4

NCBI GB Accession Number

GABRA4

Host or Source

Rabbit

Protein Name

Gamma-aminobutyric acid receptor subunit alpha-4

Nucleotide Accession Number

NM_000809

Peptide Sequence

MVSAKKVPAIALSAGVSFALLRFLCLAVCLNESPGQNQKEEKLCTENFTR

Subunit

Alpha-4

Frequently Asked Questions

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