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CHRNA5 Antibody - middle region : Biotin (ARP34967_T100-Biotin)

Product Specifications

Gene Name

Cholinergic receptor, nicotinic, alpha 5 (neuronal)

Gene Aliases

LNCR2

Gene ID

1138

Swiss Prot

P30532

Accession Number

NP_000736

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CHRNA5

Target

Nicotinic acetylcholine receptors (nAChRs), such as CHRNA5, are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero) pentamers composed of homologous subunits.

Partner Proteins

UBC; CANX; CHRNB4

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

53kDa

References & Citations

Groot-Kormelink, P.J., et al., (2001) Br. J. Pharmacol. 134 (4), 789-796

Shipping Conditions

Wet Ice

Protein Length

468

NCBI Gene Symbol

CHRNA5

NCBI GB Accession Number

CHRNA5

Host or Source

Rabbit

Protein Name

Neuronal acetylcholine receptor subunit alpha-5

Nucleotide Accession Number

NM_000745

Peptide Sequence

DGSQVDIILEDQDVDKRDFFDNGEWEIVSATGSKGNRTDSCCWYPYVTYS

Subunit

Alpha-5

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