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CACNB1 Antibody - N-terminal region : FITC (ARP34954_P050-FITC)

Selected Variant

ARP34954_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Calcium channel, voltage-dependent, beta 1 subunit

Gene Aliases

CAB1, CCHLB1, CACNLB1

Gene ID

782

Swiss Prot

Q02641

Accession Number

NP_000714

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CACNB1

Target

CACNB1 belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.

Partner Proteins

SRPK1; APP; ATN1; NEDD4L; UBC; REM1; DYNLL1; CACNA1A

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 93%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

66kDa

References & Citations

Olsen, J.V., (2006) Cell 127 (3), 635-648

Shipping Conditions

Wet Ice

Protein Length

598

NCBI Gene Symbol

CACNB1

NCBI GB Accession Number

CACNB1

Host or Source

Rabbit

Protein Name

Voltage-dependent L-type calcium channel subunit beta-1

Nucleotide Accession Number

NM_000723

Peptide Sequence

DWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSS

Subunit

Beta-1

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