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SCNN1B Antibody - C-terminal region : Biotin (ARP34936_P050-Biotin)

Product Specifications

Gene Name

Sodium channel, non-voltage-gated 1, beta subunit

Gene Aliases

BESC1, ENaCb, SCNEB, LIDLS1, ENaCbeta

Gene ID

6338

Swiss Prot

P51168

Accession Number

NP_000327

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human SCNN1B

Target

When expressed in the bladder epithelium, the protein encoded by the SCNN1B gene might be implicated in the mechanosensory transduction in the bladder afferent pathways, thereby inducing detrusor instability by outlet obstruction. Common variants of this gene confer susceptibility to human essential hypertension.

Partner Proteins

NEDD4L; SERP1; SCNN1G; SCNN1A; COMMD1; UBC; USP2; RAF1; NEDD4; TSC22D3; SGK1; EPN1; AP1M2; NFASC; CNTN1; WWP2; SCNN1D; ANK3; STX1A; ITCH; HECW1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 93%; Horse: 92%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 93%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

70kDa

References & Citations

Snyder, P.M., et al., (2004) J. Biol. Chem. 279 (44), 45753-45758

Shipping Conditions

Wet Ice

Protein Length

640

NCBI Gene Symbol

SCNN1B

NCBI GB Accession Number

SCNN1B

Host or Source

Rabbit

Protein Name

Amiloride-sensitive sodium channel subunit beta

Nucleotide Accession Number

NM_000336

Peptide Sequence

QPDTAPRSPNTGPYPSEQALPIPGTPPPNYDSLRLQPLDVIESDSEGDAI

Subunit

Beta

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