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PKD2 Antibody - N-terminal region : Biotin (ARP34930_P050-Biotin)

Selected Variant

ARP34930_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Polycystic kidney disease 2 (autosomal dominant)

Gene Aliases

PC2, PKD4, Pc-2, APKD2, TRPP2

Gene ID

5311

Swiss Prot

Q13563-4

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human PKD2

Target

This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.

Partner Proteins

MAGEA8; PLSCR1; KRTAP10-3; KRTAP10-8; KRT40; PKD1; GOLGA2; CANX; ATP1A1; UBC; PACS2; HAX1; TRPC1; TNNI3; PACS1; CD2AP; DIAPH1; TPM1; PKD2; ACTN2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 86%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

71kDa

Shipping Conditions

Wet Ice

Protein Length

646

NCBI Gene Symbol

PKD2

NCBI GB Accession Number

PKD2

Host or Source

Rabbit

Protein Name

Polycystin-2

Peptide Sequence

GLRGLWGTRLMEESSTNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSN

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