CLCNKB Antibody - C-terminal region : Biotin (ARP34917_P050-Biotin)
Product Specifications
Gene Name
Chloride channel, voltage-sensitive Kb
Gene Aliases
CLCKB, ClC-K2, ClC-Kb
Gene ID
1188
Swiss Prot
P51801
Accession Number
NP_000076
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human CLCNKB
Target
Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III Bartter Syndrome. CLCNKA and CLCNKB are closely related (94% sequence identity), tightly linked (separated by 11 kb of genomic sequence) and are both expressed in mammalian kidney.
Partner Proteins
Dlg4
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 85%; Guinea Pig: 77%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 93%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
76kDa
References & Citations
Gorgojo, J.J., et al., (2006) Horm. Res. 65 (2), 62-68
Shipping Conditions
Wet Ice
Protein Length
687
NCBI Gene Symbol
CLCNKB
NCBI GB Accession Number
CLCNKB
Host or Source
Rabbit
Protein Name
Chloride channel protein ClC-Kb
Nucleotide Accession Number
NM_000085
Peptide Sequence
ILAAGCPTEPVTLKLSPETSLHEAHNLFELLNLHSLFVTSRGRAVGCVSW
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