DIDO1 Antibody - N-terminal region: FITC (ARP34883_P050-FITC)
Product Specifications
Gene Name
Death inducer-obliterator 1
Gene Aliases
BYE1, DIO1, DATF1, DIDO2, DIDO3, DIO-1, DATF-1, C20orf158, dJ885L7.8
Gene ID
11083
Swiss Prot
Q9BTC0-3
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human DIDO1
Target
Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms.
Partner Proteins
UBC; WWOX; RPA3; RPA2; RPA1; EED; BMI1; HECW2; SRPK2; KCNK4; ARAF; Dlg4; H2AFY; U2AF1; SON; RPL18A; KRT7; APP; PCDHA2; H2AFY2; GNL3; RRS1; SIRT7; SUMO2; WWP2; WWP1; DVL3; SRSF1; HNRNPK
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purified
Concentration
0.5 mg/mL
Homology
Cow: 93%; Dog: 86%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 92%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
61kDa
Shipping Conditions
Wet Ice
Protein Length
562
NCBI Gene Symbol
DIDO1
Protein Name
Death-inducer obliterator 1
Curated Selection
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