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CNBP Antibody - N-terminal region : Biotin (ARP34815_P050-Biotin)

Product Specifications

Gene Name

CCHC-type zinc finger, nucleic acid binding protein

Gene Aliases

DM2, ZNF9, CNBP1, PROMM, RNF163, ZCCHC22

Gene ID

7555

Swiss Prot

P62633

Accession Number

NP_003409

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CNBP

Target

CNBP is a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

UBC; EZH2; BMI1; SUZ12; RNF2; BZW2; FERMT2; PFAS; EIF6; HSPA9; DFFA; MAPK14; PAN2; VCAM1; ITGA4; KCND3; Mis12; Cnbp; ZWINT; MYH4; FKTN; PCBP2; RPL31; HNRNPA3; BRIX1; APOBEC3C; RBMX; RSL1D1; RPL36; HNRNPUL1; EBNA1BP2; IGF2BP3; IGF2BP1; SYNCRIP; HNRNPR; DAP

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

19kDa

References & Citations

Gerbasi, V.R. (2007) Mol. Cell Proteomics 6 (6), 1049-1058

Shipping Conditions

Wet Ice

Protein Length

177

NCBI Gene Symbol

CNBP

NCBI GB Accession Number

CNBP

Host or Source

Rabbit

Protein Name

Cellular nucleic acid-binding protein

Nucleotide Accession Number

NM_003418

Peptide Sequence

SSNECFKCGRSGHWARECPTGGGRGRGMRSRGRGGFTSDRGFQFVSSSLP

Frequently Asked Questions

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