SRY Antibody - middle region: FITC (ARP34794_P050-FITC)
Product Specifications
Gene Name
Sex determining region Y
Gene Aliases
TDF, TDY, SRXX1, SRXY1
Gene ID
6736
Swiss Prot
Q05066
Accession Number
NP_003131
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SRY
Target
SRY is an intronless gene that encodes for a transcription factor, which is a member of the high mobility group (HMG) -box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome) ; translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG) -box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome) ; translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
Olig2; Utf1; Tcf12; Sp1; Pou3f3; Pax3; Jun; Hhex; Egr2; Dlx5; Cebpa; WDR5; SMAD3; HDAC3; KPNB1; EP300; Xpo4; ZNF208; SLC9A3R2; AR
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
SRY is supported by BioGPS gene expression data to be expressed in 721_B
Concentration
0.5 mg/mL
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
24kDa
Shipping Conditions
Wet Ice
Protein Length
204
NCBI Gene Symbol
SRY
Protein Name
Sex-determining region Y protein
Nucleotide Accession Number
NM_003140
Curated Selection
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