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THRA Antibody - middle region : HRP (ARP34780_P050-HRP)

Product Specifications

Gene Name

Thyroid hormone receptor, alpha

Gene Aliases

AR7, EAR7, ERBA, CHNG6, ERBA1, NR1A1, THRA1, THRA2, ERB-T-1, c-ERBA-1

Gene ID

7067

Swiss Prot

P10827

Accession Number

NP_003241

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human THRA

Target

The THRA gene encodes a protein that is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone.

Partner Proteins

L3MBTL3; AMOTL2; RANBP9; NCOR1; PTGES3; THRA; RXRA; FOXJ1; CLIC1; C1D; NCOR2; BUB3; tat; GTF2B; ARID5A; SUMO1; SUMO3; MED1; NRIP1; MED21; CDK7; MED25; RGN; CUL1; SEPP1; TBL1XR1; HDAC3; SMC1A; XRCC5; TBL1X; PRKDC; LIG3; HSPA4; GPS2; XRCC6; PARP1; EMD; GRIP

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that THRA is expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

55kDa

Shipping Conditions

Wet Ice

Protein Length

490

NCBI Gene Symbol

THRA

NCBI GB Accession Number

THRA

Host or Source

Rabbit

Protein Name

Thyroid hormone receptor alpha

Nucleotide Accession Number

NM_003250

Peptide Sequence

DQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVV

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