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UHRF2 Antibody - N-terminal region : Biotin (ARP34772_P050-Biotin)

Product Specifications

Gene Name

Ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase

Gene Aliases

NIRF, URF2, RNF107, TDRD23

Gene ID

115426

Swiss Prot

Q96PU4

Accession Number

NP_690856

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human UHRF2

Target

UHRF2 encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis.

Partner Proteins

UBE2D1; UBC; TP53; UHRF2; TRIM27; E2F1; MPG; SMAD4; ZNF131; SUMO1; UBE2I; ATXN1; USP7; TWF2; TRIM8; RBCK1; TFAP4; PCNP; CDK2; CCNE1; UHRF1; EHMT2; HIST1H3A; SUMO2; DNMT3B; DNMT3A; DNMT1; CDK1; CD27; CCNB1; CCNA2; BCL2L1; CCND1; BAX; BCAR1; YY1; SKP1; RB1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

90kDa

References & Citations

Li, Y., et al., (2004) Biochem. Biophys. Res. Commun. 319 (2), 464-468

Shipping Conditions

Wet Ice

Protein Length

802

NCBI Gene Symbol

UHRF2

NCBI GB Accession Number

UHRF2

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase UHRF2

Nucleotide Accession Number

NM_152896

Peptide Sequence

TNKLDSVPSTSNSDCVAADEDVIYHIQYDEYPESGTLEMNVKDLRPRART

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