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RBPJL Antibody - middle region : Biotin (ARP34710_P050-Biotin)

Product Specifications

Gene Name

Recombination signal binding protein for immunoglobulin kappa J region-like

Gene Aliases

RBPL, SUHL, RBPSUHL

Gene ID

11317

Swiss Prot

Q5QPV0

Accession Number

NP_055091

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RBPJL

Target

RBPJL is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein. In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2) . RBPJL is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2) . The protein encoded by this gene is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.

Partner Proteins

APP

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

RBPJL is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

57kDa

References & Citations

Beres, T.M., (2006) Mol. Cell. Biol. 26 (1), 117-130

Shipping Conditions

Wet Ice

Protein Length

517

NCBI Gene Symbol

RBPJL

NCBI GB Accession Number

RBPJL

Host or Source

Rabbit

Protein Name

Recombining binding protein suppressor of hairless-like protein

Nucleotide Accession Number

NM_014276

Peptide Sequence

TIIGTESVEFSFSTSLACTLEPVTPVPLISTLELSGGGDVATLELHGENF

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