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PAX5 Antibody - N-terminal region : Biotin (ARP34686_P050-Biotin)

Product Specifications

Gene Name

Paired box 5

Gene Aliases

ALL3, BSAP

Gene ID

5079

Swiss Prot

Q02548

Accession Number

NP_057953

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PAX5

Target

The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.

Partner Proteins

TBP; RB1; EP300; RUNX1; TLE4; DAXX; KPNA1; KPNA2; ID2; ID3; CREBBP; MYB; PAX5; ETS1; EBF1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

PAX5 is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

42kDa

References & Citations

Robichaud, G.A., et al., (2004) J. Biol. Chem. 279 (48), 49956-49963

Shipping Conditions

Wet Ice

Protein Length

391

NCBI Gene Symbol

PAX5

NCBI GB Accession Number

PAX5

Host or Source

Rabbit

Protein Name

Paired box protein Pax-5

Nucleotide Accession Number

NM_016734

Peptide Sequence

CVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWE

Frequently Asked Questions

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