MID1 Antibody - C-terminal region: FITC (ARP34680_T100-FITC)

MID1 is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Several different transcript variants are generated by alternate splicing; however, the full length nature of two variants has not been determined.

STK36; MID2; UBE2E3; DYRK4; UBE2E2; UBE2E1; UBE2D3; UBE2D2; UBE2D1; PKN1; PPP2R4; PPP2CA; MID1; MEOX1; FKBP1A; EHHADH; BYSL; TCEANC; UBTD1; OTUB2; GMCL1; HTT; IGBP1; PNKP; MID1IP1; GNB2L1; RPS8; RPS3; NPM1; HSP90AA1; EEF1A1; ANXA2; UBC; UBE2D4; UBE2N; ELA

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.