TRIM8 Antibody - middle region : Biotin (ARP34624_P050-Biotin)
Product Specifications
Gene Name
Tripartite motif containing 8
Gene Aliases
GERP, RNF27
Gene ID
81603
Swiss Prot
Q9BZR9
Accession Number
NP_112174
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human TRIM8
Target
This protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.
Partner Proteins
BRAP; TRIM25; PCGF5; MSL2; RNF141; TRIM2; USP7; TP53; CCNH; OTUB2; USP21; USP39; USP2; TNFAIP3; UBE2D2; TRIM47; TRIM15; TRIM8; RAD18; TRIM39; RNF111; RC3H2; RNF138; RNF181; RCHY1; RNF41; TRIM43; UHRF2; TRIM9; RNF7; TRIM24; RNF113A; MKRN3; TRAF5; TRIM21; S
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
61kDa
References & Citations
Carinci, F., (2007) Transl Res 150 (4), 233-245
Shipping Conditions
Wet Ice
Protein Length
551
NCBI Gene Symbol
TRIM8
NCBI GB Accession Number
TRIM8
Host or Source
Rabbit
Protein Name
Probable E3 ubiquitin-protein ligase TRIM8
Nucleotide Accession Number
NM_030912
Peptide Sequence
QSVPLYPCGVSSSGAEKRKHSTAFPEASFLETSSGPVGGQYGAAGTASGE
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