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METTL3 Antibody - C-terminal region : Biotin (ARP34591_P050-Biotin)

Selected Variant

ARP34591_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Methyltransferase like 3

Gene Aliases

M6A, IME4, Spo8, MT-A70, hMETTL3

Gene ID

56339

Swiss Prot

Q86U44

Accession Number

NP_062826

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human METTL3

Target

This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.

Partner Proteins

UBC; METTL14; UBD

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

METTL3 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

64kDa

Shipping Conditions

Wet Ice

Protein Length

580

NCBI Gene Symbol

METTL3

NCBI GB Accession Number

METTL3

Host or Source

Rabbit

Protein Name

N6-adenosine-methyltransferase 70 kDa subunit

Nucleotide Accession Number

NM_019852

Peptide Sequence

KIELFGRPHNVQPNWITLGNQLDGIHLLDPDVVARFKQRYPDGIISKPKN

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