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SMARCA2 Antibody - middle region: FITC (ARP34484_P050-FITC)

Product Specifications

Gene Name

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 and 4

Gene Aliases

BRM, SNF2, SWI2, hBRM, NCBRS, Sth1p, BAF190, SNF2L2, SNF2LA, hSNF2a

Gene ID

6595; 6597

Swiss Prot

P51531P51532

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SMARCA2

Target

SMARCA2 is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.

Partner Proteins

SDCBP; BEND7; UBC; SMURF2; EED; BMI1; SOX2; UL29; tat; SS18; SSX2; EPAS1; ARID1A; CBX5; PSMB2; ACTL6A; ARID1B; SEPT11; PHF10; NCOR1; SEC22B; SLC9A3R2; TOP2B; SMARCE1; SMARCD3; SMARCD2; SMARCD1; SMARCC2; SMARCC1; SMARCB1; SMARCA4; BMX; CEBPB; SIRT7; DPF1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

32kDa

Shipping Conditions

Wet Ice

Specificity

100% homologous to both isoforms of SMARCA2 and all 5 isoforms of SMARCA4

Protein Length

278

NCBI Gene Symbol

SMARCA2

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