EGLN2 Antibody - N-terminal region : Biotin (ARP34483_P050-Biotin)

Product Specifications

Gene Name

Egl nine homolog 2 (C. elegans)

Gene Aliases

EIT6, PHD1, EIT-6, HPH-1, HPH-3, HIFPH1, HIF-PH1

Gene ID

112398

Swiss Prot

Q96KS0

Accession Number

NP_444274

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human EGLN2

Target

The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. EGLN2 encodes an enzyme responsible for this posttranslational modification. Alternative splicing of EGLN2 results in three transcript variants encoding different isoforms.

Partner Proteins

SRPK2; CEP192; IKBKG; FAM46A; EPAS1; A2M; MAGEA11; SIAH2; LPP; WTIP; AJUBA; LIMD1; TRIP6; SPRY2; PRPF19; EGLN3; EGLN2; HIF1A; HIF3A; MOB4; POLR2A

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 93%; Guinea Pig: 86%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 79%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.