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RRN3 Antibody - middle region: Biotin (ARP34463_T100-Biotin)

Product Specifications

Gene Name

RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)

Gene Aliases

TIFIA, A-270G1.2

Gene ID

54700

Swiss Prot

Q9NYV6

Accession Number

NP_060897

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RRN3

Target

In mammals, growth-dependent regulation of RNA polymerase I (Pol I) transcription is mediated by RRN3, an essential initiation factor. It interacts with Pol I in the absence of template DNA, augments Pol I transcription in vivo and rescues transcription in extracts from growth-arrested cells in vitro.

Partner Proteins

UBC; ACTA1; Polr1e; POLR1B; EIF3L; NMI; RBM15; UBD; Trim28; ELAVL1; TAF1D; POLR1A; MYO1C; TAF1C; TAF1B; TAF1A; UBTF; TBP; PPP2R2A; CDK2; CCNE1; RIBIN; ACTB

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Sample Type

RRN3 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/mL

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

74kDa

Shipping Conditions

Wet Ice

Protein Length

650

NCBI Gene Symbol

RRN3

Protein Name

RNA polymerase I-specific transcription initiation factor RRN3

Nucleotide Accession Number

NM_018427

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