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RRN3 Antibody - middle region : Biotin (ARP34463_T100-Biotin)

Selected Variant

ARP34463_T100-Biotin

Size: 100 µL

Product Specifications

Gene Name

RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)

Gene Aliases

TIFIA, A-270G1.2

Gene ID

54700

Swiss Prot

Q9NYV6

Accession Number

NP_060897

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RRN3

Target

In mammals, growth-dependent regulation of RNA polymerase I (Pol I) transcription is mediated by RRN3, an essential initiation factor. It interacts with Pol I in the absence of template DNA, augments Pol I transcription in vivo and rescues transcription in extracts from growth-arrested cells in vitro.

Partner Proteins

UBC; ACTA1; Polr1e; POLR1B; EIF3L; NMI; RBM15; UBD; Trim28; ELAVL1; TAF1D; POLR1A; MYO1C; TAF1C; TAF1B; TAF1A; UBTF; TBP; PPP2R2A; CDK2; CCNE1; RIBIN; ACTB

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Sample Type

RRN3 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

74kDa

References & Citations

Miller, G., et al., (2001) EMBO J. 20 (6), 1373-1382

Shipping Conditions

Wet Ice

Protein Length

650

NCBI Gene Symbol

RRN3

NCBI GB Accession Number

RRN3

Host or Source

Rabbit

Protein Name

RNA polymerase I-specific transcription initiation factor RRN3

Nucleotide Accession Number

NM_018427

Peptide Sequence

VDGKVDNGKTKDLYRDLINIFDKLLLPTHASCHVQFFMFYLCSFKLGFAE

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