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VPS24 Antibody - N-terminal region : HRP (ARP34452_P050-HRP)

Selected Variant

ARP34452_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Charged multivesicular body protein 3

Gene Aliases

NEDF, VPS24, CGI-149

Gene ID

51652

Swiss Prot

Q3ZTS9

Accession Number

NP_057163

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human VPS24

Target

VPS24 encodes a protein that acts in the sorting of transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily.

Partner Proteins

STAMBP; SMAD5; SMAD1; ATP6V1B1; APP; UBD; CHMP4B; CHMP3; CHMP2A; CHMP2B; TNPO3; RAB11A; CHMP4A; VAV2; UBC; VTA1; VPS4A; IGFBP7

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

25kDa

References & Citations

Whitley, P., et al., (2003) J Biol Chem. 278 (40), 38786-95

Shipping Conditions

Wet Ice

Protein Length

222

NCBI Gene Symbol

CHMP3

NCBI GB Accession Number

CHMP3

Host or Source

Rabbit

Protein Name

Charged multivesicular body protein 3

Nucleotide Accession Number

NM_016079

Peptide Sequence

RVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVCIVLAKEMIRSRKAVSKL

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