What sizes are available for NSD2 Antibody - N-terminal region : HRP (ARP34429_T100-HRP)?

NSD2 Antibody - N-terminal region : HRP (ARP34429_T100-HRP) is available in the following size(s): 100 µL.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

NSD2 Antibody - N-terminal region : HRP (ARP34429_T100-HRP)

Q: What is the catalog number for NSD2 Antibody - N-terminal region : HRP (ARP34429_T100-HRP)?

The catalog number for NSD2 Antibody - N-terminal region : HRP (ARP34429_T100-HRP) is ARP34429_T100-HRP.

Product Specifications

Gene Name

Nuclear receptor binding SET domain protein 2

Gene Aliases

WHS, TRX5, KMT3F, KMT3G, MMSET, WHSC1, REIIBP

Gene ID

7468

Swiss Prot

P22415

Accession Number

NP_009053

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human USF1

Target

This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t (4;14) (p16.3; q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.

Partner Proteins

HIST1H3A; HIST3H3; HDAC1; TRIM28; UBC; SF3A1; HNRNPR; MPHOSPH10; RAD50; SART3; NUP93; GTF3C4; NOLC1; DDX21; BAZ1B; DDX18; KHSRP; RRP1; SMARCA5; SMC1A; RBM10; XRCC5; VIM; EZR; TOP2B; TOP1; TMPO; SMARCA4; SFPQ; RPN1; RBBP4; RANGAP1; PTBP1; PRKDC; PLRG1; PKP

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

Sample Type

WHSC1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

34kDa

References & Citations

Shoulders, C.C. et al., (2004) Nat. Genet. 36 (4), 322-323

Shipping Conditions

Wet Ice

Protein Length

310

NCBI Gene Symbol

NSD2

NCBI GB Accession Number

NSD2

Host or Source

Rabbit

Protein Name

Histone-lysine N-methyltransferase NSD2

Nucleotide Accession Number

NM_007122

Peptide Sequence

DPTSVAIASIQSAATFPDPNVKYVFRTENGGQVMYRVIQVSEGQLDGQTE

Frequently Asked Questions

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