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CBX1 Antibody - N-terminal region : FITC (ARP34426_P050-FITC)

Product Specifications

Gene Name

Chromobox homolog 1

Gene Aliases

CBX, M31, MOD1, p25beta, HP1-BETA, HP1Hsbeta, HP1Hs-beta

Gene ID

10951

Swiss Prot

P83916

Accession Number

NP_006798

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CBX1

Target

CBX1 is the component of heterochromatin. CBX1 recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. CBX1 interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the in

Partner Proteins

PRDM6; SUMO1; UBC; RNF2; PARK2; NR2F6; VHL; EHMT2; ABI3BP; VTN; TRIM39; CBX5; HIST1H3B; KLF11; HIST3H3; PCNA; MECP2; ADNP; POGZ; ADNP2; CBX3; TRIM28; CHAF1A; HIST1H4F; XRCC6; CHD4; H2AFB1; NSL1; SUMO2; HIST1H3A; Mad2l2; Cbx1; DNMT3B; ZNF382; H3F3A; SUV420

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

CBX1 is supported by BioGPS gene expression data to be expressed in OVCAR3

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

21kDa

References & Citations

Ayoub, N., (er) Nature (2008) In press

Shipping Conditions

Wet Ice

Protein Length

185

NCBI Gene Symbol

CBX1

NCBI GB Accession Number

CBX1

Host or Source

Rabbit

Protein Name

Chromobox protein homolog 1

Nucleotide Accession Number

NM_006807

Peptide Sequence

MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDN

Frequently Asked Questions

More Discoveries

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