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ZYX Antibody - middle region : HRP (ARP34387_T100-HRP)

Selected Variant

ARP34387_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

Zyxin

Gene Aliases

ESP-2, HED-2

Gene ID

7791

Swiss Prot

Q15942

Accession Number

NP_003452

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ZYX

Target

Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles.

Partner Proteins

RTN4IP1; YPEL3; IMP3; PHF21A; PDLIM5; LIN7A; SUMO1; NEDD8; FAM129B; CORO1B; CAND1; PUF60; PAPOLA; NUDC; SEC23B; SEC24C; HIST1H4A; UGP2; TARS; PXN; GART; GARS; APEH; FN1; HIPK3; VCAM1; UBC; UBL7; UFC1; UBXN7; ZC3H7B; TTLL12; FERMT2; TOMM34; AHCYL1; SSSCA1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Sample Type

ZYX is strongly supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 85%; Dog: 92%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 85%; Rabbit: 92%; Rat: 91%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

61kDa

References & Citations

Li, B., et al., (2004) J. Biol. Chem. 279 (19), 20401-20410

Shipping Conditions

Wet Ice

Protein Length

572

NCBI Gene Symbol

ZYX

NCBI GB Accession Number

ZYX

Host or Source

Rabbit

Protein Name

Zyxin

Nucleotide Accession Number

NM_003461

Peptide Sequence

GSPQPPSFTYAQQREKPRVQEKQHPVPPPAQNQNQVRSPGAPGPLTLKEV

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