ZYX Antibody - middle region : FITC (ARP34387_T100-FITC)
Product Specifications
Gene Name
Zyxin
Gene Aliases
ESP-2, HED-2
Gene ID
7791
Swiss Prot
Q15942
Accession Number
NP_003452
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human ZYX
Target
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles.
Partner Proteins
RTN4IP1; YPEL3; IMP3; PHF21A; PDLIM5; LIN7A; SUMO1; NEDD8; FAM129B; CORO1B; CAND1; PUF60; PAPOLA; NUDC; SEC23B; SEC24C; HIST1H4A; UGP2; TARS; PXN; GART; GARS; APEH; FN1; HIPK3; VCAM1; UBC; UBL7; UFC1; UBXN7; ZC3H7B; TTLL12; FERMT2; TOMM34; AHCYL1; SSSCA1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Sample Type
ZYX is strongly supported by BioGPS gene expression data to be expressed in HeLa
Concentration
0.5 mg/ml
Homology
Cow: 85%; Dog: 92%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 85%; Rabbit: 92%; Rat: 91%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
61kDa
References & Citations
Li, B., et al., (2004) J. Biol. Chem. 279 (19), 20401-20410
Shipping Conditions
Wet Ice
Protein Length
572
NCBI Gene Symbol
ZYX
NCBI GB Accession Number
ZYX
Host or Source
Rabbit
Protein Name
Zyxin
Nucleotide Accession Number
NM_003461
Peptide Sequence
GSPQPPSFTYAQQREKPRVQEKQHPVPPPAQNQNQVRSPGAPGPLTLKEV
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