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CHD4 Antibody - N-terminal region : FITC (ARP34372_P050-FITC)

Product Specifications

Gene Name

Chromodomain helicase DNA binding protein 4

Gene Aliases

CHD-4, Mi-2b, SIHIWES, Mi2-BETA

Gene ID

1108

Swiss Prot

Q14839

Accession Number

NP_001264

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CHD4

Target

CHD4 is a probable transcription regulator.The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

SUMO2; SUMO3; DNMT3B; DNMT1; NACC2; UBC; LGR4; RPA3; RPA2; RPA1; EED; RNF2; SUZ12; BMI1; GATAD2A; HDAC2; HDAC1; MTA3; CSNK2A1; HIST3H3; VCAM1; ITGA4; NOTCH1; ESR1; TBL1XR1; MBD3; MTA2; SMARCC1; RBBP7; RBBP4; CHD3; SNAI1; SNAI2; SUMO1; NEDD8; MTA1; NR2C2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that CHD4 is expressed in OVCAR3

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

218kDa

References & Citations

Sillibourne, J.E., (2007) Mol. Biol. Cell 18 (9), 3667-3680

Shipping Conditions

Wet Ice

Protein Length

1912

NCBI Gene Symbol

CHD4

NCBI GB Accession Number

CHD4

Host or Source

Rabbit

Protein Name

Chromodomain-helicase-DNA-binding protein 4

Nucleotide Accession Number

NM_001273

Peptide Sequence

QKKERMLLCRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKL

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