COLQ Antibody - N-terminal region : Biotin (ARP34362_P050-Biotin)
Product Specifications
Gene Name
Collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
Gene Aliases
EAD, CMS5
Gene ID
8292
Swiss Prot
Q9Y215-8
Accession Number
NP_536805
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human COLQ
Target
COLQ encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in COLQ are associated with endplate acetylcholinesterase deficiency.
Partner Proteins
UBC; MUSK; BCHE; ACHE
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 86%; Horse: 93%; Human: 100%; Mouse: 92%; Rabbit: 93%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
34kDa
References & Citations
Ishigaki, K., et al., (2003) Neuromuscul. Disord. 13 (3), 236-244
Shipping Conditions
Wet Ice
Protein Length
329
NCBI Gene Symbol
COLQ
NCBI GB Accession Number
COLQ
Host or Source
Rabbit
Protein Name
Acetylcholinesterase collagenic tail peptide
Nucleotide Accession Number
NM_080544
Peptide Sequence
LQLFFLSIVSQPTFINSVLPISAALPSLDQKKRGGHKACCLLTPPPPPLF
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